Walk into a serious bodybuilding gym today and performance-enhancing drugs are discussed like ordinary locker-room chatter, a topic once treated like a secretive underground exchange. Testosterone, anabolic steroids, growth-hormone drugs, and an expanding menu of peptides have become familiar vocabulary among men chasing bigger muscles, lower body fat, and faster recovery.
Only if this were mere gym gossip. A recent study of 718 fitness-center members in the Netherlands, published in Drug Testing and Analysis by Stubbe et al, found that conventional questioning produced an overall performance-enhancing drug prevalence of just 0.4%. But when researchers used a method designed to make respondents more comfortable admitting sensitive behavior, the estimate jumped to 8.2%. Therefore, the researchers concluded that direct questioning substantially underestimated use.
Without importing the Dutch percentages as US benchmarks, the study is useful evidence that conventional surveys substantially underestimate PED use in fitness settings. The finding holds for the US and supports skepticism toward low self-report numbers from direct questioning.
And so?
Well, if people don’t tell researchers what they are taking, official surveys can make the phenomenon look considerably smaller than it really is.
Peptides Have Changed the Conversation
Steroids are now only part of a larger equation in the modern enhancement market. Peptides have brought another layer, particularly compounds marketed around muscle growth, recovery, fat loss and hormone manipulation.
The word “peptide” can make something sound inherently sophisticated or harmless, but it isn’t. The FDA has specifically warned about compounds including BPC-157, CJC-1295, and ipamorelin. The agency cited limited human safety information and, for some substances, concerns involving immune reactions, impurities, and serious adverse events.
The agency’s concerns have real teeth. In June 2026, the FDA warned a peptide seller that products including gonadorelin and another marketed compound were unapproved new drugs, stressing that injectable products can bypass some of the body’s defenses against contaminants and create potentially serious risks.
Meanwhile, FDA advisory discussions in July 2026 included BPC-157, TB-500, and other peptides being considered for possible compounding use. That does not mean these substances have been established as safe bodybuilding treatments. It shows how rapidly the market is moving into territory where scientific evidence, medical oversight and consumer demand are colliding.
The Health Bill Can Arrive Later
Here is where the gym-culture conversation often gets uncomfortable. A man can see bigger shoulders, a thicker chest, and dramatic changes in the mirror long before he sees the consequences.
High blood pressure, blood clots, heart attacks, stroke, liver problems, and reduced sperm production have shown up on NIDA’s list of potential consequences associated with anabolic steroid misuse. Likewise, the FDA has linked bodybuilding products containing steroids or steroid-like substances to serious liver injury, kidney damage, heart attack, stroke, and blood clots.
So, the real conversation isn’t whether every muscular man is using drugs. He isn’t, by the way. The issue is that performance-enhancing drug use has become so rampant—visible enough, accessible enough, and normalized enough—that pretending it is merely an obscure fringe behavior no longer fits the evidence.
This story was originally published by Men’s Journal on Aug 15, 2026, where it first appeared in the Fitness section. Add Men’s Journal as a Preferred Source by clicking here.



