Chemyo Review: INSIDE10 for 10% Off

Who Are Chemyo?

Chemyo is arguably the first company that is recalled when someone references selective androgen receptor modulators (SARMs).

Chemyo is an American firm based in Wilmington, Delaware. It is known for its high-quality SARMs and reliability within a niche that often operates in a gray area.

Are Chemyo’s Products Legal?

Yes, Chemyo’s products/SARMs are legal in the US because they are being marketed as research chemicals.

However, SARMs are not approved by the Food and Drug Administration (FDA) outside of research. Therefore, SARMs are illegal to sell or purchase in the US when promoted for enhancing body composition.

Chemyo’s SARMs are also legal in the UK if being sold for research. However, the Medicines and Healthcare Products Regulatory Agency (MHRA) has not approved SARMs for public use. Thus, similar to the US, marketing them as dietary supplements is illegal.

In Australia, the Therapeutic Goods Act 1989 prohibits the sale of SARMs without a doctor’s prescription.

Individuals should check the legal status of SARMs in their own country before ordering.

What Are the Benefits of Chemyo?

Over 99% Purity

Every SARM from Chemyo is typically formulated at over 99% purity due to their recrystallization techniques, which yield higher purities (Brunner et al., 2020).

Chemyo provides third-party certificates of analysis (COAs) to customers, confirming the purity of its products. We have also observed positive results from Chemyo’s SARMs, indicating that the compounds listed on the label are present.

There are different types of SARM companies:

• Companies that provide high-quality products that are worth paying for.
• Those that are more affordable and thus more likely to contain diluted compounds and lower purities.

Chemyo falls into the former category, alongside reputable brands like Swiss Chems, which guarantee over 99% purity.

An investigative study conducted by the Journal of the American Medical Association found the following after purchasing 44 SARM products online (Van Wagoner et al., 2017):

• 52% of the products contained SARMs.
• 25% contained hidden compounds that were not written on the label.
• 9% did not have a detectable substance.
• 59% contained differing substance quantities compared to what was specified on the bottle.

These statistics reinforce the importance of sourcing SARMs from a legitimate supplier with verified and recent third-party COAs.

Competitive Pricing

When factoring in Chemyo’s high-purity levels, their SARMs are competitively priced. However, they appear more expensive than rival companies due to their bottles containing 67% more volume than the industry standard.

International Shipping

In our experience, high-quality SARM companies are becoming increasingly reluctant to ship overseas due to packages being delayed or seized.

Chemyo, however, does ship internationally to:

• Canada
• The United Kingdom
• Some North American, South American, and African countries.

Although Chemyo does not appear to ship to Europe at this time, excluding the UK.

Free Shipping

Customers are entitled to free shipping when US orders are at least $100+, and non-US orders are at least $275.

In our experience, Chemyo’s shipping is relatively prompt:

• We have had US orders arrive in 3–5 days.
• Our international orders to our UK location took 5 days.

A Variety of Payment Options

Chemyo offers an array of payment options, which currently are as follows:

• Checkbook: 5% discount
• Solana: 5% discount
• Credit or debit card via Max Redemption or Verified-Pay: 7.95% fee
• Bitcoin: 10% discount
• Zelle: 7.95% fee

Bitcoin is the most economical way to pay for SARMs from Chemyo, although this payment method does not suit everyone.

An Established Brand

We have found Chemyo to be an honest and ethical company that has consistently produced effective SARMs for several years.

Thus, Chemyo is not a new or obscure SARMs brand where researchers will worry about their package not arriving.

Chemyo has accumulated a vast customer base, the majority of whom are pleased with their products.

Prompt Customer Support

Chemyo’s 24/7 live chat support has responded to our queries within minutes. We have also tested their response time via email. On August 6, 2025, at 01:46 am, we asked if Chemyo provides wholesale or dropshipping options. They replied on August 6 at 02.53 am, exactly 1 hour and 7 minutes later.

If researchers have an urgent matter, they will receive a faster response from Chemyo through the live chat function on their website.

Bitcoin Discount

Chemyo offers researchers a 10% discount when paying with Bitcoin or other cryptocurrencies. Pure Rawz and Sports Technology Labs also provide a 10% discount. However, other companies, such as Swiss Chems, do not offer any savings with this payment method.

Disclosure: We do not accept any form of advertising on Inside Bodybuilding. We monetize our practice via doctor consultations and carefully chosen supplement recommendations, which have given our patients excellent results.

Maximum Chemyo Discount

10% discount code: Inside10

What Are the Drawbacks of Chemyo?

7.95% Credit Card Fee

A 7.95% credit card fee is a drawback for thrifty customers seeking maximum savings.

While it is not a major issue for some, the fact that other SARM companies charge less for credit card transactions is a disadvantage.

No Peptides

Several other SARM companies offer peptide products, such as BPC-157 and TB-500. However, Chemyo has not taken this approach.

Chemyo previously discontinued its LGD-4033 product; however, it is now available for purchase again under the name LGD-4.

No Stealth Shipping

In our experience, Chemyo’s packaging is not discreet, which benefits their credibility. However, this lack of discretion poses challenges for successfully delivering international orders.

Although our items arrived in the UK in less than two weeks, some researchers have reported significant delays at customs. This includes delivery times extending up to a month or even resulting in seizures.

If you are a native US citizen, Chemyo’s shipping is typically straightforward and swift. However, because of their transparent and intentional packaging, non-US researchers may experience some delays.

Chemyo Reviews on Facebook

Researchers have published the following Chemyo reviews in our Facebook group.

MK-677 from Chemyo made a significant difference in my muscle fullness and vascularity. I’m hungry all the time, but I feel great. Pumps in the gym are very noticeable, and my muscles have grown notably.

Chemyo has great quality products, and you get more quantity for your money. I have never heard anyone have a negative experience with Chemyo. I am currently administering their LGD-4033, and it’s amazing.

I have been taking RAD-140 from Chemyo for the last 3 months at only 10 mg a day, and it is powerful.

I’ve used the MK-2866 and MK-677 value pack before and had excellent results with stamina, muscle hardness, and muscle growth. Now I’m hoping to experience similar improvements with their MK-677 and LGD-4033. I’ll keep the group updated. But yes, very good SARMs, and I would highly recommend either them or Sport Asylum.

Chemyo is the best and a legitimate company. I just ordered my second bottle of Ostarine from them; great customer service and fast delivery.

I have used Chemyo and Rat’s Army and had impressive results. Researchers won’t be disappointed.

Should Researchers Purchase From Chemyo?

Chemyo is one of the best SARM companies, based on the purity and efficacy of their products.

However, Chemyo can improve by correcting the following:

• 7.95% credit card fee
• 7.95% Zelle fee
• Lack of peptide products

Are There More Suitable Alternatives?

Sports Technology Labs is an alternative source that offers peptides and does not include a credit card fee at checkout.

Sports Technology Labs Advantages:

• 0% credit card fee
• Over 98% purity, confirmed with COAs
• Slightly lower prices than Chemyo
• 10% cryptocurrency discount
• Peptides in stock
• Excellent, fast customer support
• 15% discount codes are available, compared to 10% for Chemyo

Sports Technology Labs Disadvantages:

• Does not ship outside of the US
• No capsule SARMs

Thus, US researchers could achieve additional savings when ordering from Sports Technology Labs while receiving the same high-quality products.

However, Chemyo is the superior option for those based in Canada or other non-US countries, as it offers international shipping.

What Visual Changes Can Researchers Expect?

This is a Chemyo customer’s transformation after utilizing a conservative cycle of RAD-140, consisting of 10 mg/day for 7 weeks. However, these before-and-after photos only showcase the results observed after the first 30 days.

Following his 7-week cycle, he reported gaining:

• 13 pounds in total weight
• 50 pounds on his bench press
• 30 pounds on his squat
• 40 pounds on his deadlift

How Are Chemyo’s Products Administered?

Preclinical Research

Researchers are advised to administer Chemyo’s liquid SARMs using the following steps:

1. Measure the required dose using the mL markings on the dropper.
2. Insert a specialized gavage needle or tube into the rat’s esophagus and deliver the solution into the stomach.

Clinical Research

During human trials, researchers can administer Chemyo’s SARMs to subjects by:

1. Measuring the liquid
2. Establishing the correct dose with a marked dropper
3. Placing it in the subject’s mouth for swallowing

Frequently Asked Questions

Can Chemyo’s Products Decrease Testosterone Levels?

A 2025 systematic review on PubMed associated SARMs with endogenous testosterone suppression (Vasireddi et al., 2025). Additional National Library of Medicine research concluded that SARMs impair male reproductive physiology, causing negative effects on spermatogenesis (Whitaker et al., 2021). This is the medical term for sperm production.

How Can Researchers Normalize Their Hormones?

The National Library of Medicine researchers stated that the following medications aid in spermatogenesis recovery:

• Selective estrogen receptor modulators (SERMs)
• Human chorionic gonadotropin (hCG)
• Aromatase inhibitors (AIs)
• Recombinant follicle-stimulating hormone (rFSH)

Thus, post-cycle therapy (PCT) is effective in restoring the function of the hypothalamic-pituitary-testicular axis (HPTA).

How Much Suppression Can Be Experienced?

An individual’s level of testosterone suppression varies depending on their unique response to the compounds used and the dosages administered.

Some patients do not experience any deterioration in well-being after administering Chemyo’s Ostarine or RAD-140, even though their total testosterone levels have dropped significantly. If the HPTA is impaired, individuals can be prescribed hCG post-cycle to increase endogenous testosterone production. However, this is not necessary if their mood and energy levels remain normal.

Other patients experience decreased libido, anxiety, or fatigue post-cycle. These side effects are often the result of using more potent compounds such as S23 or YK-11. In such cases, PCT is especially beneficial.

Dr. George Touliatos says that, in his experience, “SARMs do typically cause testosterone suppression, despite their tissue-selective mechanisms.” He recommends that users employ PCT to restore their HPTA function following SARM cycles.

Can Chemyo’s Products Affect Cholesterol or Liver Enzymes?

Dr. Touliatos adds that SARMs also cause dyslipidemia (abnormal levels of fat in the blood) and elevated liver enzymes. Consequently, he likens their effects to those of Anavar. Based on Dr. Touliatos’ clinical experience, YK-11 is a particularly hepatotoxic SARM, which he has observed to cause hypertransaminasemia (high liver enzymes) on numerous occasions.

Users can adopt a diet high in unsaturated fats to treat elevated low-density lipoprotein (LDL) cholesterol levels during SARM cycles. Additionally, researchers can incorporate regular cardiovascular training during supplementation to:

• Decrease systolic pressure
• Increase blood flow to the heart

Tauroursodeoxycholic acid (TUDCA) supplementation can improve liver health during SARM use, with a dose of 500 mg/day providing hepatoprotective effects. 600 mg/day of N-acetylcysteine (NAC) can also decrease elevated alanine aminotransferase (ALT) and aspartate aminotransferase (AST) enzymes by reducing oxidative stress.

Victor Martinez, the 2007 Arnold Classic champion, has experience with SARMs and states that they are effective for enhancing body composition. However, he warns against continuous use to reduce the risk of long-term issues, suggesting that cyclic usage is more optimal for health. Martinez also emphasizes the importance of medical supervision when taking any performance-enhancing substance to monitor organ health and potential hormone fluctuations.

Can Fertility Be Impacted?

Dr. Justin Dubin, an author of several research articles published in the Journal of Sexual Medicine, says SARMs not only reduce testosterone levels but also impact fertility in some users.

Users may improve their fertility following SARM cycles by administering hCG, which stimulates spermatogenesis and endogenous testosterone production. A dose of 1,000 IU of hCG, taken daily for 30 days post-cycle, is recommended to normalize sperm and hormone health.

What is the Price of Chemyo’s Compounds?

What Are the Potential Benefits of Chemyo’s Products?

Based on existing studies, SARMs increase:

• Muscle hypertrophy
• Muscular strength
• Endurance
• Fat loss

How Do Chemyo’s Products Work?

SARMs enhance anabolism, or muscle building, through androgen receptor stimulation. This consequently increases protein synthesis and nitrogen retention in muscle cells.

Some SARMs improve endurance by enhancing mitochondrial efficiency and stimulating erythropoiesis, the process of producing red blood cells. This contributes to increased energy production and oxygen delivery to the muscles, delaying the time it takes to fatigue.

Certain SARMs enhance fat loss by:

• Increasing metabolic rate
• Suppressing appetite
• Enhancing fat oxidation

Are Chemyo’s Products Safe? Potential Side Effects

SARMs are not considered safe for human use, as they have not yet received FDA approval and have limited clinical research available.

Dr. Mike Israetel says that SARMs induce toxic effects comparable to anabolic steroids. Therefore, the notion of SARMs being a safe alternative to anabolic steroids is not entirely accurate. Dr. Israetel adds that users are taking risks with SARMs due to their unregulated nature and the many counterfeit products existing on the market.

The side effects of SARMs can be unique to the individual taking them, with Victor Martinez stating that he experienced blurry vision during supplementation, whereas other users maintain optimal ocular health.

While some studies and case reviews have described SARMs as safe in certain contexts, they have also caused toxic effects in others. A summary of some of the research conducted on SARMs is provided below.

LGD-4033

A randomized controlled trial found LGD-4033 to be well-tolerated in 76 healthy men after receiving dosages of 0.1, 0.3, or 1 mg per day for 21 days. The Journals of Gerontology concluded that LGD-4033 “was safe” despite observing reductions in high-density lipoprotein (HDL) and testosterone. They reported no changes in AST or ALT (Basaria et al., 2013).

Research has shown that drinking carbonated water can increase HDL and decrease LDL levels, with carbon dioxide acting as a vasodilator. Therefore, consuming carbonated water is recommended for individuals using LGD-4033 or other SARMs.

RAD-140

Clinical Breast Cancer researchers found RAD-140 to have an “acceptable safety profile” following doses of 50 mg, 100 mg, and 150 mg per day. However, raised liver enzymes, vomiting, dehydration, and decreased appetite were reported as some of the side effects (LoRusso et al., 2022).

This data illustrates the percentage of RAD-140 users who experienced elevated levels of AST, ALT, and total blood bilirubin. These increases were following dosages of 50, 100, and 150 mg/day in the study conducted by LoRusso et al.

Users are advised to supplement with TUDCA or NAC to reduce hepatotoxicity during RAD-140 supplementation, increase water intake to prevent dehydration, and add the following spices to stimulate appetite:

• Black pepper
• Mint
• Ginger
• Cinnamon

Ostarine

During a study published in the Journal of Cachexia, Sarcopenia and Muscle, Ostarine was administered to 120 men over the age of 60 for 12 weeks. A dosage of 3 mg/day did not produce more notable side effects compared to the placebo group (Dalton et al., 2011).

YK-11

A Chemico-Biological Interactions study in rats found that 0.35 g/kg of YK-11 altered hippocampal neurochemistry, resulting in memory impairment (Dahleh et al., 2024). Thus, YK-11 exhibits neurotoxic effects, causing damage to the brain. The researchers also observed increases in the cytokines IL-1β and IL-6 following YK-11 administration. These are small proteins that influence immunity, indicating heightened inflammation and oxidative stress.

For researchers seeking to reduce neurotoxicity during YK-11 cycles, they may supplement with benfotiamine. Benfotiamine is a highly bioavailable form of vitamin B1 that:

• Decreases oxidative stress
• Improves nerve conduction
• Inhibits neurodegeneration

MK-677

Elsevier reported that 25 mg/day of MK-677, administered over two 14-day periods, did not cause any notable side effects (Murphy et al., 1998). It was described as “generally well-tolerated.”

Cardarine

When administered in high dosages and for extended durations, this peroxisome proliferator-activated receptor delta (PPARδ) agonist has been shown to cause cancer in mice. In other studies, doses of 10 mg/kg and 30 mg/kg of Cardarine inhibited tumorigenicity in female mice with nasopharyngeal carcinoma, a type of throat cancer.

Frontiers in Pharmacology states that Cardarine achieved this effect by suppressing cell division at the G2/M phase and promoting apoptosis, otherwise known as cell death (Ji et al., 2018). Currently, there is a lack of data regarding the carcinogenic effects of Cardarine in humans.

Cardarine users may support their immune health by supplementing with vitamin D3 (cholecalciferol). Vitamin D3 has been shown to promote anticarcinogenesis by enhancing the immune system’s production of killer cells, also known as T cells and NK cells. Administering 4,000 IU (100 mcg) of vitamin D3 daily has proven effective in reducing the incidence of illness among our patients.

S4

S4 can cause transient ocular changes in some patients, resulting in a yellow tint to their vision. However, permanent vision alterations following supplementation discontinuation are uncommon.

Researchers utilizing S4 may counteract vision deterioration by enhancing eye health with the following supplements:

• Vitamin A: 3,000 IU (900 mcg) per day
• Lutein: 10 mg per day
• Zeaxanthin: 2 mg per day

S23

In preclinical research published in Endocrinology, S23 temporarily impaired spermatogenesis (sperm production) in rats. This effect occurred due to S23 decreasing luteinizing hormone (LH) and follicle-stimulating hormone (FSH) (Jones et al., 2009). This effect was shown to be reversible following S23 treatment, which is promising for safety.

For accelerated spermatogenesis recovery following S23 cycles, researchers may supplement with the following natural herbs for 30 days:

• Tribulus terrestris: 1,500 mg per day
• Maca root: 1,500 mg per day
• Ashwagandha extract: 600 mg per day

How Can Researchers Contact Chemyo?

• Email: Support@chemyo.com
• Address: 4023 Kennett Pike STE 59371, Wilmington, Delaware, 19807, USA
• Phone: +1 302 543 2011

Does Chemyo Have a Refund Policy?

Chemyo responds to refund requests on a case-by-case basis.

Can Chemyo’s Products Cause an Athlete to Fail a Drug Test?

Yes, SARMs are banned in various sporting organizations, including:

• World Anti-Doping Agency (WADA)
• United States Anti-Doping Agency (USADA)
• International Olympic Committee (IOC)

In WADA’s experience with testing for SARMs, they state that positive tests increased sixfold between 2016 and 2020.

Athletes should consult with their respective governing bodies to verify whether SARMs are prohibited in their sport.

One of the highest-profile athletes found with SARMs in his system is boxer Ryan Garcia. The New York State Athletic Commission reported a failed drug test in the lead-up to Garcia’s fight with Devin Haney. However, Garcia stated that an amino acid and carbohydrate supplement he was taking was contaminated, containing trace amounts of Ostarine. He later took a plea deal, was suspended for one year, and received a fine of $1.1 million.

Joakim Noah was banned by the National Basketball Association (NBA) for 20 games after he was found taking LGD-4033. Noah said he regretted taking the SARM and that it was an ethical mistake on his part.

This chart, according to USADA, indicates the number of SARM doping violations since 2012.

Athletes can send samples of their supplements to third-party laboratories for analysis, ensuring that no hidden substances could result in a failed drug test in their respective sports.

Summary: Is Chemyo Reliable?

Chemyo is a reliable source for researchers based in the United States, as there are typically no issues with their domestic shipping.

However, Chemyo does not offer discreet shipping. Therefore, overseas orders are less reliable due to an increased risk of customs seizures. Nonetheless, we have not experienced any issues receiving several packages at our UK location.

Important Information

• SARMs are intended solely for research purposes and are not approved for human consumption (Joshi et al., 2025).
• The European Journal of Clinical Pharmacology states that SARMs pose health risks similar to those of anabolic steroids (Leciejewska et al., 2024).
• Individuals contemplating the use of SARMs or other performance-enhancing substances are advised to consult a healthcare professional before proceeding.
• Chemyo’s SARMs should be kept out of the reach of children.
• The content written in this Chemyo review does not constitute medical advice.
• Users should have blood tests to monitor their health during and after supplementation.
• Researchers who purchase Chemyo’s SARMs from a non-official source may receive a counterfeit product.
• Women who are pregnant or lactating should not utilize any of Chemyo’s products.
• Researchers should inspect the expiration date on Chemyo bottles prior to administration.
• Inside Bodybuilding is not responsible for any ill effects suffered by users purchasing from Chemyo.
• The results depicted in this review by Chemyo customers are individual experiences and may vary.

Researchers can view Chemyo’s purity test results for their products in the table below. The respective COAs are also available on the Chemyo website. Mobile users can scroll to the right to access all the data.

Co Authors :

Dr. O’Connor has over 20 years of experience treating men and women with a history of anabolic steroid, SARM, and PED use. He has been a board-certified MD since 2005 and provides guidance on harm reduction methodologies.

Dr. O’Connor is a clinical instructor at the University of Connecticut School of Medicine and has been featured in various media publications, including Generation Iron, Dr. Phil, National Geographic, The New York Times, Muscle and Fitness, and others.

Dr. O’Connor also co-authored the largest survey on anabolic steroid use, involving 2,385 men, published in the peer-reviewed American Journal of Men’s Health.

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