{"id":1297,"date":"2025-12-28T06:07:11","date_gmt":"2025-12-28T06:07:11","guid":{"rendered":"https:\/\/worldbodybuildingnews.com\/?p=1297"},"modified":"2025-12-28T06:07:11","modified_gmt":"2025-12-28T06:07:11","slug":"cycle-updates-do-glp1s-actually-work-or-is-it-overhyped-are-myostatin-inhibitors-real","status":"publish","type":"post","link":"https:\/\/worldbodybuildingnews.com\/?p=1297","title":{"rendered":"Cycle Updates, Do GLP1s Actually Work Or Is It Overhyped? Are Myostatin Inhibitors Real?"},"content":{"rendered":"<p><iframe loading=\"lazy\"  width=\"580\" height=\"385\" src=\"https:\/\/www.youtube.com\/embed\/FxigEHpL68Q\" frameborder=\"0\" allowfullscreen><\/iframe><\/p>\n<p><strong>Video Source:<\/strong> <a href=\"https:\/\/www.youtube.com\/watch?v=FxigEHpL68Q\" target=\"_blank\" rel=\"nofollow noopener\">Watch on YouTube<\/a><\/p>\n<p>Join IFBB Pro Big Paul for a Live Q&#038;A <\/p>\n<p>\ud83d\udce7 For exclusive inside Information, join The Anabolic Mail List: https:\/\/www.anabolicbodybuilding.com\/email-list<\/p>\n<p>\ud83d\udcaaTEAM ANABOLIC BODYBUILDING &#8211; Members Only Community: https:\/\/www.skool.com\/teamanabolicbodybuilding\/about<\/p>\n<p>\ud83c\udf93THE SCIENCE OF ANABOLICS E-COURSE &#8211; Free Preview<br \/>\nhttps:\/\/www.anabolicbodybuilding.com\/the-science-of-anabolics-performance-enhancing-drugs<\/p>\n<p>\ud83d\uddfa\ufe0f Get The Ultimate Cycle Cheat Sheet: https:\/\/www.anabolicbodybuilding.com\/cheatsheet<\/p>\n<p>FOLLOW:<br \/>\n\ud83e\udd18 Instagram: https:\/\/www.instagram.com\/paulkbarnett\/<br \/>\n\ud83d\udd08 Spotify: https:\/\/open.spotify.com\/show\/3PKOCKSDh6ZeaLmVoHF60z<br \/>\n\ud83c\udd87 Formerly Twitter: https:\/\/twitter.com\/paulb3rd<\/p>\n<p>0:00:00 &#8211; Intro<br \/>\n0:02:26 &#8211; Updates On Big Paul\u2019s Training Post-Surgery<br \/>\n0:04:17 &#8211; Would Big Paul Want To Compete?<br \/>\n0:05:03 &#8211; Current Physique Update<br \/>\n0:06:43 &#8211; Thoughts On Clients Eating Chicken Thighs During Contest Prep<br \/>\n0:07:55 &#8211; What Can You Consider High ALT?<br \/>\n0:08:28 &#8211; Thoughts On MOTS-c &#038; Reta<br \/>\n0:09:01 &#8211; EQ Can Crush E2<br \/>\n0:09:58 &#8211; Thoughts On People Trying To Take Down Mike Israetel<br \/>\n0:12:07 &#8211; Thoughts On Unilateral Training While Training<br \/>\n0:13:04 &#8211; Do You Need To Change Your Training Routine? + Thoughts On The Bro Split<br \/>\n0:14:05 &#8211; What Pro Show Would Paul Want To Do?<br \/>\n0:16:17 &#8211; How Hard Should You Cut Before A Rebound?<br \/>\n0:17:50 &#8211; What\u2019s The Ideal LDL Level?<br \/>\n0:19:23 &#8211; How Long Should A Diet Break Be?<br \/>\n0:19:56 &#8211; When Do You Start Seeing Results From HGH?<br \/>\n0:20:26 &#8211; Do You Get High Prolactin From Nandrolone Or Tren?<br \/>\n0:22:17 &#8211; How To Deal With Clients With An Adaptable Metabolism<br \/>\n0:23:28 &#8211; When Should You Stop A Bulk?<br \/>\n0:24:13 &#8211; Big Paul Had A Lot Of Water Retention Recently<br \/>\n0:25:41 &#8211; How To Deal With Golfers Elbow<br \/>\n0:26:50 &#8211; Can People Be Non-Responders To BP Meds?<br \/>\n0:29:23 &#8211; What Is The Ideal Fat Loss Per Week?<br \/>\n0:30:10 &#8211; Does Paul Like Using A Gi During Jujitsu?<br \/>\n0:32:38 &#8211; Thoughts On Test, NPP &#038; HGH Cycle<br \/>\n0:33:47 &#8211; How Much Muscle Can You Hold On To If You Stopped Gear?<br \/>\n0:36:51 &#8211; Thoughts On MOTS-c &#038; SLU In The Offseason<br \/>\n0:38:21 &#8211; How Would Anadrol Affect Blood Work?<br \/>\n0:38:59 &#8211; How To Know Your Response To Androgens<br \/>\n0:39:49 &#8211; What\u2019s The Upper Limit Of Reta For A Client?<br \/>\n0:40:13 &#8211; Differences Between MOTS-c &#038; Reta<br \/>\n0:41:21 &#8211; Should You Inject Daily? + How Quickly Do You Go Back To Maintenance Cals?<br \/>\n0:42:23 &#8211; Who\u2019s Going To Come Out With Real Follistatin?<br \/>\n0:43:01 &#8211; Favorite Supplement Brands<br \/>\n0:43:41 &#8211; Thoughts On Elevated BP From Test, EQ &#038; NPP<br \/>\n0:44:13 &#8211; There Are Multiple Pathways For Muscle Growth<br \/>\n0:47:16 &#8211; Thoughts On Mitochondrial Peptides<br \/>\n0:48:20 &#8211; Will Paul Be At The Arnold?<br \/>\n0:49:01 &#8211; Story On Phil Heath Becoming A Pro On 300mg Deca<br \/>\n0:49:37 &#8211; Most People Never Make It Past The Intermediate Lifter Stage<br \/>\n0:51:11 &#8211; Can Overweight Guys Use HGH?<br \/>\n0:52:09 &#8211; Thoughts On GHK-Cu<br \/>\n0:54:47 &#8211; Thoughts On Combining NPP + Tren &#038; Their Effects On Sleep<br \/>\n0:56:34 &#8211; Software Recommendatios For Bodybuilding Apps<br \/>\n0:57:13 &#8211; Thoughts On HRV<br \/>\n0:57:51 &#8211; Thoughts On Steroids\u2019 Effects On The Brain<br \/>\n0:59:45 &#8211; Thoughts On Myostatin Inhibitors<br \/>\n1:02:08 &#8211; Does Reta Actually Work Or Is It Overhyped?<br \/>\n1:04:56 &#8211; A Lot Of Other Peptides Are Being Overhyped<br \/>\n1:07:17 &#8211; Wrapping Up! Paul\u2019s Blocking All The Weirdos!<br \/>\n1:09:04 &#8211; Will There Be Coaching Discounts For Christmas?<br \/>\n1:10:20 &#8211; Closing Thoughts<\/p>\n<p>WARNING<br \/>\n========<br \/>\nThe Video has been made available for entertainment and educational purposes only. I do not make any warranties to the accuracy, applicability, fitness, or completeness of the content. <\/p>\n<p>The content is not intended to be a substitute for professional medical or legal advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider. Never disregard professional medical advice or delay in seeking it because of something you have seen on this channel.<\/p>\n<p>I hereby disclaim any and all liability to any party for any direct, indirect, implied, punitive, special, incidental, or other consequential damages arising directly or indirectly from any use of the content, which is provided as is, and without warranties.<\/p>\n<p>\ud83c\udf99\ufe0f New to streaming or looking to level up? Check out StreamYard and get $10 discount! \ud83d\ude0d https:\/\/streamyard.com\/pal\/d\/6129714795905024<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Video Source: Watch on YouTube Join IFBB Pro Big Paul for a Live Q&#038;A \ud83d\udce7 For exclusive inside Information, join The Anabolic Mail List: https:\/\/www.anabolicbodybuilding.com\/email-list \ud83d\udcaaTEAM ANABOLIC BODYBUILDING &#8211; Members Only Community: https:\/\/www.skool.com\/teamanabolicbodybuilding\/about \ud83c\udf93THE SCIENCE OF ANABOLICS E-COURSE &#8211; Free Preview https:\/\/www.anabolicbodybuilding.com\/the-science-of-anabolics-performance-enhancing-drugs \ud83d\uddfa\ufe0f Get The Ultimate Cycle Cheat Sheet: https:\/\/www.anabolicbodybuilding.com\/cheatsheet FOLLOW: \ud83e\udd18 Instagram: https:\/\/www.instagram.com\/paulkbarnett\/ \ud83d\udd08 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1298,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"video","meta":{"tdm_status":"","tdm_grid_status":"","footnotes":""},"categories":[1],"tags":[],"class_list":{"0":"post-1297","1":"post","2":"type-post","3":"status-publish","4":"format-video","5":"has-post-thumbnail","7":"category-news","8":"post_format-post-format-video"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Cycle Updates, Do GLP1s Actually Work Or Is It Overhyped? 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Are Myostatin Inhibitors Real? - World Bodybuilding News\" \/>\n<meta property=\"og:description\" content=\"Video Source: Watch on YouTube Join IFBB Pro Big Paul for a Live Q&#038;A \ud83d\udce7 For exclusive inside Information, join The Anabolic Mail List: https:\/\/www.anabolicbodybuilding.com\/email-list \ud83d\udcaaTEAM ANABOLIC BODYBUILDING &#8211; Members Only Community: https:\/\/www.skool.com\/teamanabolicbodybuilding\/about \ud83c\udf93THE SCIENCE OF ANABOLICS E-COURSE &#8211; Free Preview https:\/\/www.anabolicbodybuilding.com\/the-science-of-anabolics-performance-enhancing-drugs \ud83d\uddfa\ufe0f Get The Ultimate Cycle Cheat Sheet: https:\/\/www.anabolicbodybuilding.com\/cheatsheet FOLLOW: \ud83e\udd18 Instagram: https:\/\/www.instagram.com\/paulkbarnett\/ \ud83d\udd08 [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/worldbodybuildingnews.com\/?p=1297\" \/>\n<meta property=\"og:site_name\" content=\"World Bodybuilding News\" \/>\n<meta property=\"article:published_time\" content=\"2025-12-28T06:07:11+00:00\" \/>\n<meta name=\"author\" content=\"1wilburn\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"1wilburn\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/worldbodybuildingnews.com\\\/?p=1297#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/worldbodybuildingnews.com\\\/?p=1297\"},\"author\":{\"name\":\"1wilburn\",\"@id\":\"https:\\\/\\\/worldbodybuildingnews.com\\\/#\\\/schema\\\/person\\\/3f1ebf7578fb8e614291f27a298dd3a3\"},\"headline\":\"Cycle Updates, Do GLP1s Actually Work Or Is It Overhyped? 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